'Melatonin prevents and delays chemical carcinogenisis and cancer growth in vivo in the mouse and rat. Blind people have robust, albeit mostly free-running melatonin circadian rhythms and they are at lower risk for the development of many, if not all, cancers. Women with breast cancer and men with prostate cancer have diminished nighttime melatonin secretion.'
Tuesday, 25 August 2015
Glutamine. Everyone forgets about glutamine...
'... in many cancer cells, glutamine is the primary mitochondrial substrate and is required to maintain mitochondrial membrane potential and integrity as well as support of the NADPH production needed for redox control and macromolecular synthesis.'
This is why a restricted ketogenic diet for cancer management must restrict protein. Therapeutic fasts can also be potentially very useful.
Sunday, 23 August 2015
Next month will be very special for me. After 2 and a half years of recovery both mentally and physically from my brain haemorrhage that led to my cancer diagnosis and the subsequent problems associated with that I am finally ready to go back to my studies. It's a huge thing for me and a big step as I still have invisible disabilities that affect me on a day to day basis despite my vast improvements I have made symptomatically and through positive scan results.
I have made the decision to study Human and Medical Science full time at the University of Westminster where my studies were cruelly cut short by this disease. Going back will feel quite surreal as I honestly never thought it would be possibly and I was unsure of my short term future but here I am! I still don't look too far into the future but I am realistically optimistic.
I feel as though I can make a real difference with my studies and hope to push through with my own research through my personal experiences and my understanding of epigenetics. I have already decided to focus my degree on neurological disease management and will approach cancer as a metabolic disease as I have done with my own treatment since I voluntarily chose to stop my ineffective chemotherapy a year and a half ago.
I'm incredibly excited about this opportunity and I can't wait to start. I see this as being the best avenue for me in order to be a proactive patient advocate.
Wednesday, 12 August 2015
'Unlike skeletal muscle, heart muscle functions almost exclusively aerobically, as evidenced by the density of mitochondria in heart muscle. Moreover, the heart has virtually no glycogen reserves. Fatty acids are the heart's main source of fuel, although ketone bodies as well as lactate can serve as fuel for heart muscle. In fact, heart muscle consumes acetoacetate in preference to glucose.'- Biochemistry. 5th edition. 2002